Extracellular matrix degrading enzymes at the prostasome surface
نویسندگان
چکیده
منابع مشابه
Single microassay for matrix degrading enzymes.
Matrix degrading enzymes are implicated in several disease processes such as abdominal aortic aneurysms and emphysema, however, monitoring proteolytic activity in a single assay is not well-established. Numerous assays have been developed to measure matrix degrading enzymes, which use artificial substrates or substrates derived from natural substrate protein. We have recently developed an assay...
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Cell interactions with extracellular matrices are important to pathological changes that occur during cell transformation and tumorigenesis. Several extracellular matrix proteins including fibronectin, thrombospondin-1, laminin, SPARC, and osteopontin have been suggested to modulate tumor phenotype by affecting cell migration, survival, or angiogenesis. Likewise, proteases including the matrix ...
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ژورنال
عنوان ژورنال: Prostate Cancer and Prostatic Diseases
سال: 2005
ISSN: 1365-7852,1476-5608
DOI: 10.1038/sj.pcan.4500828